The mission of the Macular Pigment Research Group is to study the role of nutrition for optimising visual function and prevention of blindness, cognitive function and prevention of Alzheimer’s disease.
The Macular Pigment Research Group (MPRG) is based in Carriganore House, Waterford Institute of Technology, Waterford, Ireland. This unique research facility offers state-of-the-art vision testing laboratories and infrastructure. In addition, we have a high quality biochemical laboratory, which allows us to conduct clinical trials to the highest possible standard.
The focus of our research concerns naturally occurring plant pigments known as carotenoids. Carotenoids play important roles throughout the body, but three particular carotenoids (lutein, zeaxanthin and meso-zeaxanthin) are found at the back of the eye (the macula) where they are collectively known as macular pigment.
Prof. Stephen Beatty
L.R.C.P.I., L.R.C.S.I., M.B., B.Ch., B.A.O.(N.U.I.), M.M.Sc., F.R.C.Ophth, E.B.O.D., M.D. - Director
Mr. Kwadwo Owusu Akuffo
O.D. - Postgraduate Research Student
Ms. Jessica Dennison
Postgraduate Research Student
Ms. Kate Loskutova
Visiting Medical Research Student
Ms. Fiona Moejes
Visiting PhD Student
Macular Pigment Research Group Overview 2012
An Taoiseach, Mr Enda Kenny TD Launches MPRG Vision Research Centre at WIT
MPRG Biochemical Laboratory
Macular Pigment Research Group, Vision Research Centre
Macular pigment and its functions
RTE Nationwide (Ireland)- Dr. John Nolan and Prof. Stephen Beatty
Part 1 of RTE Nationwide Programme on Macular Pigment Research Group
Part 2 of RTE Nationwide Programme on Macular Pigment Research Group
There are no current vacancies at the MPRG at this time.
An sprioc atá ag an Grúpa Taighde Lí Macúl ná chun staideár a dhéanamh ar an ról atá ag cothú chun feidhmiú amharc a bharrfheabhsaigh agus daille a sheachaint, feidhm cognaíoch agus galar Alzheimer a sheachaint.
Tá an Grúpa Taighde Lí Macúl lonnaithe i Tigh Carraiganore, Institiúid Teicneolaíochta Phort Láirge, Port Láirge, Éire. Chuireann an fóntas taighde uathúil seo tástáil radharc saotharlanna agus bonneagar atá faoi staid na teicníochta ar fáil. Chomh maith leis sin, tá saotharlann bithcheimiceach againn anseo, agus tugann sé deis dúinn trialacha cliniciúil a iompair chuig an chaighdeán is airde.
Tá ár taighde dírithe ar líonna plandaí a tharlaíonn go nádúrtha. Glaotar caratéanóideacha ar na líonna sin.. Tá ról tábhachtach ag na caratéinóideacha i gcorp an dhuine, ach tá trí caratéinóideacha ar leith (lutein, zeaxanthin agus méisea-zeaxanthin) a fhaightear ag cúl na súile (an macúl), in áit ina aithnítear iad mar lí macúil.
Faigheann an Trialacha Forlíonú Saibhriú Reitinach Láir (TFSRL) mhaoinithe tríd an Comhairle Taighde Eorpach, agus tá dhá trialacha éagsúla i gceist leis: Gnáth TFSRL agus MMA TFSRL. An sprioc atá ag TFSRL ná chun tionchar de lí macúil saibhrithe ar cruthú radharc agus daille a mheas le gach ceann do na trí caratéanóideacha – lutein (L), zeaxanthin (Z), agus méisea-zeaxanthin (MZ). Is é seo an chéad imscrúdú a rinne tástáil ar na tionchar do forlíonú le gach ceann do na trí caratéanóideacha macúil, MZ san áireamh, i gcomhthéacs de go leor cumhacht, dall dúbailte, randamaithe, triail cliniciúil ina bhfuil rialaithe ag placebo.
Triail 1: Gnáth TFSRL (Níl níos mó earcú ar fail don triail seo)
Tá muid ag iarraidh oibrí deonach do Gnáth TFSRL. Tá an triail seo ag imscrúdú slite ina mbíonn tionchar ag saibhriú lí macúil le na caratéanóideacha macúil (lutein, zeaxanthin agus méisea-zeaxanthin) ar cruthú radharc agus ar taithí do gnáth ábhair. Tá muid ag iarraidh 120 n-ábhair a n-earcú i ngach grúpa. An imscrúdaitheoir GTLM atá bainteach leis an triail seo ná dalta PhD Jessica Dennison.
Na dhaoine atá oiriúnach mar oibrithe deonach ná:
Dhaoine thar 18
Dhaoine gan aon ríochtaí súile (is féidir le spéaclaí agus chaitheamhóirí lionsa tadhaill an obair deonach a dhéanamh)
Dhaoine nach bhfuil ag tógáil forlíontaí cothaithe ina bhfuil baintach le súile faoin tráth seo (sin é forlíontaí a chuimsíonn lutein, zeaxanthin agus/nó méisea-zeaxanthin)
Níl dhaoine le diaibéiteas nó dhaoine atá tar éis máinliacht léasar na súile a fháil oiriúnach don triail seo.
Le do thoil, chuir gloach ar Niamh Owens ar 051 302810, nó, chuir ríomhphoist chuig email@example.com
Triail 2: MMA TFSRL (Níl níos mó earcú ar fáil don triail seo)
Níl níos mó earcaíocht ar fáil do MMA TFSRL. Tá an triail seo ag imscrúdú slite ina mbíonn tionchar ag saibhriú lí macúil le na caratéanóideacha macúil (lutein, zeaxanthin agus méisea-zeaxanthin) ar cruthú radharc agus ar taithí d’ábhair le céim luath do meathlúchán macúil aoischoibhneasa (MMA). An imscrúdaitheoir GTLM atá bainteach leis an triail seo ná dalta PhD Kwadwo Akuffo.
Beidh gach rannpháirteach ar an triail an MMA TFSRL ráthaithe chun forlíon a chuimsíonn cheann do na dhá foirmlithe do na caratéanóideacha lutein, zeaxanthin, agus meso-zeaxanthin, chomh maith le vitimíní-iolrach a fháil. Leanann sé seo na treorlíntí cúram don Institúid Náisiúnta na Súile a bhaineann le othair le MMA.
Na dhaoine atá oiriúnach mar oibrithe deonach do TFSRL MMA ná:
Dhaoine thar 18
Dhaoine atá tar éis a bheith diagnóisaithe le céim luath do meathlúchán macúil aoischoibhneasa (MMA) i súil amháin
Dhaoine nach bhfuil ag tógáil forlíontaí cothaithe ina bhfuil baintach le súile faoin tráth seo (sin é forlíontaí a chuimsíonn lutein, zeaxanthin agus/nó meso-zeaxanthin)
Níl dhaoine le diaibéiteas oiriúnach don triail seo.
Le do thoil, chuir glaoch ar Laura Corcoran ar 051 845505, nó, chuir ríomhphoist chuig firstname.lastname@example.org
|Prevalence of age-related macular degeneration in the Republic of Ireland||Kwadwo Owusu Akuffo, John Nolan, Jim Stack, Rachel Moran, Joanne Feeney, Rose Anne Kenny, Tunde Peto, Cara Dooley, Aisling M O'Halloran, Hilary Cronin, Stephen Beatty||British Journal of Ophthalmology||2015|
|SUPPLEMENTATION WITH THREE DIFFERENT MACULAR CAROTENOID FORMULATIONS IN PATIENTS WITH EARLY AGE-RELATED MACULAR DEGENERATION.||Sabour-Pickett S1, Beatty S, Connolly E, Loughman J, Stack J, Howard A, Klein R, Klein BE, Meuer SM, Myers CE, Akuffo KO, Nolan JM||Retina||2014|
|Verification of Meso-Zeaxanthin in Fish||John M Nolan, Stephen Beatty, Katie A Meagher, Alan N Howard, David Kelly and David I Thurnham||Food Processing and Technology||2014|
|Central Retinal Enrichment Supplementation Trials (CREST): Design and Methodology of the CREST Randomized Controlled Trials.||Akuffo KO1, Beatty S, Stack J, Dennison J, O'Regan S, Meagher KA, Peto T, Nolan J.||Ophthalmic Epidemiol||2014|
|Measuring Visual Function Using the MultiQuity System: Comparison with an Established Device||Patrycja Smolarek-Kasprzak, John M. Nolan, Stephen Beatty, Jessica Dennison, Kwadwo Owusu Akuffo, Robert Kuchling, Jim Stack, and Graham O’Regan||Journal of Ophthalmology||2014|
|The Impact of Supplemental Macular Carotenoids in Alzheimer's Disease: A Randomized Clinical Trial.||Nolan JM, Loskutova E, Howard A, Mulcahy R, Moran R, Stack J, Bolger M, Coen RF, Dennison J, Akuffo KO, Owens N, Power R, Thurnham D, Beatty S.||Journal of Alzheimer's Disease||2014|
|Macular Pigment, Visual Function, and Macular Disease among Subjects with Alzheimer's Disease: An Exploratory Study||John Nolan Nolan JM, Loskutova E, Howard AN, Moran R, Mulcahy R, Stack J, Bolger M, Dennison J, Akuffo KO, Owens N, Thurnham DI, Beatty S||Journal of Alzheimer's Disease||2014|
|Concordance of macular pigment measurements obtained using customized heterochromatic flicker photometry, dual-wavelength autofluorescence, and single-wavelength reflectance||Dennison JL, Stack J, Beatty S, Nolan JM||Exp Eye Res||2013|
|Low macular pigment optical density is associated with lower cognitive performance in a large, population-based sample of older adults||Feeney J, Finucane C, Savva GM, Cronin H, Beatty S, Nolan JM, Kenny RA||Neurobiol Aging||2013|
|Macular pigment and its contribution to vision||Loskutova E, Nolan J, Howard A, Beatty S||Nutrients||2013|
|Visual outcome after antioxidant supplementation||Beatty S, Nolan JM, Muldrew KA, Woodside J, Stevenson MR, Chakravarthy U||Ophthalmology||2013|
|Re: lutein supplementation improves visual performance in Chinese drivers: 1-year randomized, double-blind, placebo-controlled study: the importance of supplementing with all three macular carotenoids.||Nolan J, Beatty S, Dennison J||Nutrition||2013|
|Serum response to supplemental macular carotenoids in subjects with and without age-related macular degeneration||Meagher KA, Thurnham DI, Beatty S, Howard AN, Connolly E, Cummins W, Nolan JM||Br J Nutr||2013|
|Visual performance in patients with neovascular age-related macular degeneration undergoing treatment with intravitreal ranibizumab||Sabour-Pickett S, Loughman J, Nolan JM, Stack J, Pesudovs K, Meagher KA, Beatty S||J Ophthalmol||2013|
|Response to Bernstein et al.||Nolan JM, Meagher K, Kashani S, Beatty S||Eye (Lond)||2013|
|What is meso-zeaxanthin, and where does it come from?||Nolan JM, Meagher K, Kashani S, Beatty S||Eye (Lond)||2013|
|Investigation of genetic variation in scavenger receptor class B, member 1 (SCARB1) and association with serum carotenoids||McKay GJ, Loane E, Nolan JM, Patterson CC, Meyers KJ, Mares JA, Yonova-Doing E, Hammond CJ, Beatty S, Silvestri G||Ophthalmology||2013|
|Profiles of macular pigment optical density and their changes following supplemental lutein and zeaxanthin: Letter||Nolan J, Beatty S||Invest Ophthalmol Vis Sci||2012|
|The natural history of tractional cystoid macular edema||Charalampidou S, Nolan J, Beatty S||Retina||2012|
|Education is positively associated with macular pigment: the Irish Longitudinal Study on Ageing (TILDA)||Nolan JM, Feeney J, Kenny RA, Cronin H, O'Regan C, Savva GM, Loughman J, Finucane C, Connolly E, Meagher K, Beatty S||Invest Ophthalmol Vis Sci||2012|
|The impact of macular pigment augmentation on visual performance using different carotenoid formulations||Loughman J, Nolan JM, Howard AN, Connolly E, Meagher K, Beatty S||Invest Ophthalmol Vis Sci||2012|
|A review of the evidence germane to the putative protective role of the macular carotenoids for age-related macular degeneration||Sabour-Pickett S, Nolan JM, Loughman J, Beatty S||Mol Nutr Food Res||2012|
|The heritability of macular response to supplemental lutein and zeaxanthin: a classic twin study||Hammond CJ, Liew SH, Van Kuijk FJ, Beatty S, Nolan JM, Spector TD, Gilbert CE||Invest Ophthalmol Vis Sci||2012|
|Impact of dietary carotenoid deprivation on macular pigment and serum concentrations of lutein and zeaxanthin||Loughman J, Nolan JM, Beatty S||Br J Nutr||2012|
|Secondary outcomes in a clinical trial of carotenoids with coantioxidants versus placebo in early age-related macular degeneration||Beatty S, Chakravarthy U, Nolan JM, Muldrew KA, Woodside JV, Denny F, Stevenson MR||Ophthalmology||2012|
|Macular carotenoid supplementation in subjects with atypical spatial profiles of macular pigment||Nolan JM, Akkali MC, Loughman J, Howard AN, Beatty S||Exp Eye Res||2012|
|Prognostic indicators and outcome measures for surgical removal of symptomatic nonadvanced cataract||Charalampidou S, Loughman J, Nolan J, Stack J, Cassidy L, Pesudovs K, Beatty S||Arch Ophthalmol||2011|
|26th Hohenheim consensus conference, September 11, 2010 scientific substantiation of health claims: evidence-based nutrition||Biesalski HK, Aggett PJ, Anton R, Bernstein PS, Blumberg J, Heaney RP, Henry J, Nolan JM, Richardson DP, van Ommen B, Witkamp RF, Rijkers GT, Zöllner I||Nutrition||2011|
|An evaluation of a novel instrument for measuring macular pigment optical density: the MPS 9000||Loughman J, Scanlon G, Nolan JM, O'Dwyer V, Beatty S||Acta Ophthalmol||2011|
|The association between macular pigment optical density and CFH, ARMS2, C2/BF, and C3 genotype||Loane E, Nolan JM, McKay GJ, Beatty S||Exp Eye Res||2011|
|Supplementation with all three macular carotenoids: response, stability, and safety||Connolly EE, Beatty S, Loughman J, Howard AN, Louw MS, Nolan JM||Invest Ophthalmol Vis Sci||2011|
|Estimation of effective lens position using a method independent of preoperative keratometry readings||Dooley I, Charalampidou S, Nolan J, Loughman J, Molloy L, Beatty S||J Cataract Refract Surg||2011|
|Psychophysical impact and optical and morphological characteristics of symptomatic non-advanced cataract||Charalampidou S, Nolan J, Loughman J, Stack J, Higgins G, Cassidy L, Beatty S||Eye (Lond)||2011|
|The impact of macular pigment augmentation on visual performance in normal subjects: COMPASS||Nolan JM, Loughman J, Akkali MC, Stack J, Scanlon G, Davison P, Beatty S||Vision Res||2011|
|Macular pigment: its associations with color discrimination and matching||Davison P, Akkali M, Loughman J, Scanlon G, Nolan J, Beatty S||Optom Vis Sci||2011|
|Changes in macular pigment optical density and serum concentrations of lutein and zeaxanthin in response to weight loss||Kirby ML, Beatty S, Stack J, Harrison M, Greene I, McBrinn S, Carroll P, Nolan JM||Br J Nutr||2011|
|Visual perceptions induced by intravitreous injections of therapeutic agents||Charalampidou S, Nolan J, Ormonde GO, Beatty S||Eye (Lond)||2011|
|The respective relationships between lipoprotein profile, macular pigment optical density, and serum concentrations of lutein and zeaxanthin||Loane E, Nolan JM, Beatty S||Invest Ophthalmol Vis Sci||2010|
|Update on modifiable risk factors for age-related macular degeneration||Nolan JM, O'Regan S, O'Regan G, Beatty S||Optometry in Practice||2010|
|Macular pigment optical density in an ageing Irish population: The Irish Longitudinal Study on Ageing||Nolan JM, Kenny R, O'Regan C, Cronin H, Loughman J, Connolly EE, Kearney P, Loane E, Beatty S||Ophthalmic Res||2010|
|The relationship between macular pigment and visual performance||Loughman J, Akkali MC, Beatty S, Scanlon G, Davison PA, O'Dwyer V, Cantwell T, Major P, Stack J, Nolan JM||Vision Res||2010|
|Effect on refractive outcomes after cataract surgery of intraocular lens constant personalization using the Haigis formula||Charalampidou S, Cassidy L, Ng E, Loughman J, Nolan J, Stack J, Beatty S||J Cataract Refract Surg||2010|
|Apolipoprotein E genotype is associated with macular pigment optical density||Loane E, McKay GJ, Nolan JM, Beatty S||Invest Ophthalmol Vis Sci||2010|
|Macular pigment and its contribution to visual performance and experience||Loughman J, Davison P.A, Nolan JM, Akkali M.C, Beatty S||J Optom||2010|
|A central dip in the macular pigment spatial profile is associated with age and smoking||Kirby ML, Beatty S, Loane E, Akkali MC, Connolly EE, Stack J, Nolan JM||Invest Ophthalmol Vis Sci||2010|
|Augmentation of macular pigment following supplementation with all three macular carotenoids: an exploratory study||Connolly EE, Beatty S, Thurnham DI, Loughman J, Howard AN, Stack J, Nolan JM||Curr Eye Res||2010|
|Augmentation of macular pigment following implantation of blue light-filtering intraocular lenses at the time of cataract surgery||Nolan JM, O'Reilly P, Loughman J, Stack J, Loane E, Connolly E, Beatty S||Invest Ophthalmol Vis Sci||2009|
|Risk factors for age-related maculopathy||Connell PP, Keane PA, O'Neill EC, Altaie RW, Loane E, Neelam K, Nolan JM, Beatty S||J Ophthalmol||2009|
|Psychophysical function in age-related maculopathy||Neelam K, Nolan J, Chakravarthy U, Beatty S||Surv Ophthalmol||2009|
|Foveal anatomic associations with the secondary peak and the slope of the macular pigment spatial profile||Kirby ML, Galea M, Loane E, Stack J, Beatty S, Nolan JM||Invest Ophthalmol Vis Sci||2009|
|The utility of using customized heterochromatic flicker photometry (cHFP) to measure macular pigment in patients with age-related macular degeneration||Stringham JM, Hammond BR, Nolan JM, Wooten BR, Mammen A, Smollon W, Snodderly DM||Exp Eye Res||2008|
|The rationale and evidence base for a protective role of macular pigment in age-related maculopathy||Loane E, Kelliher C, Beatty S, Nolan JM||Br J Ophthalmol||2008|
|Spatial profile of macular pigment and its relationship to foveal architecture||Nolan JM, Stringham JM, Beatty S, Snodderly DM||Invest Ophthalmol Vis Sci||2008|
|Diet and risk factors for age-related maculopathy||O'Connell ED, Nolan JM, Stack J, Greenberg D, Kyle J, Maddock L, Beatty S||Am J Clin Nutr||2008|
|Macular pigment and age-related macular degeneration: longitudinal data and better techniques of measurement are needed||Beatty S, van Kuijk FJ, Chakravarthy U||Invest Ophthalmol Vis Sci||2008|
|Transport and retinal capture of lutein and zeaxanthin with reference to age-related macular degeneration||Loane E, Nolan JM, O'Donovan O, Bhosale P, Bernstein PS, Beatty S||Surv Ophthalmol||2008|
|Measurement of macular pigment optical density using two different heterochromatic flicker photometers||Loane E, Stack J, Beatty S, Nolan JM||Curr Eye Res||2007|
|Risk factors for age-related maculopathy are associated with a relative lack of macular pigment||Nolan JM, Stack J, O' Donovan O, Loane E, Beatty S||Exp Eye Res||2007|
|The relationships between macular pigment optical density and its constituent carotenoids in diet and serum||Nolan JM, Stack J, O'Connell E, Beatty S||Invest Ophthalmol Vis Sci||2007|
|Changes in macular pigment optical density and serum concentrations of its constituent carotenoids following supplemental lutein and zeaxanthin: the LUNA study||Trieschmann M, Beatty S, Nolan JM, Hense HW, Heimes B, Austermann U, Fobker M, Pauleikhoff D||Exp Eye Res||2007|
|Macular carotenoids and age-related maculopathy||O'Connell E, Neelam K, Nolan J, Au Eong KG, Beatty S||Ann Acad Med Singapore||2006|
|Macular pigment and ocular biometry||Neelam K, Nolan J, Loane E, Stack J, O'Donovan O, Au Eong KG, Beatty S||Vision Res||2006|
|Monthly consistency of macular pigment optical density and serum concentrations of lutein and zeaxanthin||Nolan JM, Stack J, Mellerio J, Godhinio M, O'Donovan O, Neelam K, Beatty S||Curr Eye Res||2006|
|Macular pigment levels following successful macular hole surgery||Neelam K, O'Gorman N, Nolan J, O'Donovan O, Au Eong KG, Beatty S||Br J Ophthalmol||2005|
|A novel index for predicting intraocular pressure reduction following cataract surgery||Issa SA, Pacheco J, Mahmood U, Nolan J, Beatty S||Br J Ophthalmol||2005|
|Measurement of macular pigment: Raman spectroscopy versus heterochromatic flicker photometry||Neelam K, O'Gorman N, Nolan J, O'Donovan O, Wong HB, Au Eong KG, Beatty S||Invest Ophthalmol Vis Sci||2005|
|Macular pigment optical density and its relationship with serum and dietary levels of lutein and zeaxanthin||Beatty S, Nolan J, Kavanagh H, O'Donovan O||Arch Biochem Biophys||2004|
|Macular pigment and percentage of body fat||Nolan J, O'Donovan O, Kavanagh H, Stack J, Harrison M, Muldoon A, Mellerio J, Beatty S||Invest Ophthalmol Vis Sci||2004|
|Macular pigment and risk for age-related macular degeneration in subjects from a Northern European population||Beatty S, Murray IJ, Henson DB, Carden D, Koh H, Boulton ME||Invest Ophthalmol Vis Sci||2001|
|The role of oxidative stress in the pathogenesis of age-related macular degeneration||Beatty S, Koh H, Phil M, Henson D, Boulton M||Surv Ophthalmol||2000|
|Macular pigment optical density measurement: a novel compact instrument||Beatty S, Koh HH, Carden D, Murray IJ||Ophthalmic Physiol Opt||2000|
|Photocoagulation of subfoveal choroidal neovascular membranes in age related macular degeneration: the impact of the macular photocoagulation study in the United Kingdom and Republic of Ireland||Beatty S, Au Eong KG, McLeod D, Bishop PN||Br J Ophthalmol||1999|
|Macular pigment and age related macular degeneration||Beatty S, Boulton M, Henson D, Koh HH, Murray IJ||Br J Ophthalmol||1999|
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Prof Nolan spoke to Frances Shanahan from Drivetime (RTE1) about our research. Tune in at...
Prof Nolan speaks to Drivetime
Prof Nolan spoke to Frances Shanahan from Drivetime (RTE1) about our research. Tune in at 2.19 to hear the interview. http://www.rte.ie/radio/utils/radioplayer/rteradioweb.html#!rii=9%3A10376978%3A83%3A20%2D02%2D2015%3A
On Friday 20th February, Mr Paudie Coffey TD, Minister of State at the Department of...
NEW LABS TO BRING ‘BLUE SKY’ VISION RESEARCH CLOSER TO MARKET
On Friday 20th February, Mr Paudie Coffey TD, Minister of State at the Department of the Environment, opened officially two state-of-the-art laboratories at Waterford Institute of Technology’s (WIT) €4 million Vision Research Centre which houses the Macular Pigment Research Group (MPRG).
The new labs will support the MPRG’s ambition to generate viable industry for the south east by developing more efficient methods of harvesting lutein, a nutrient essential for optimal vision and protection against the world’s leading cause of blindness – Age-related Macular Degeneration (AMD).
According to Prof John Nolan, Principal Investigator of MPRG, “The global demand for lutein is growing rapidly as people begin to understand the importance of this nutrient for eye heath and general wellbeing. With the aid of our new and specialised world-class laboratories, and funding from the European Research Council (ERC), we are investigating efficient ways to generate and obtain lutein from natural sources. This is important because we are currently dependent on the marigold flower, which is highly seasonal and country dependent. If this project is successful we will greatly advance science in this area and generate opportunity for major industry in Ireland.”
Opening the new labs, Minister Coffey said, "I want to congratulate Prof John Nolan and his team in WIT. For over twelve years, the MPRG has been at the cutting edge of eye nutrition research worldwide and the group’s most recent research publications underlines the huge asset the MPRG is for this country and Waterford more specifically.
"In the last year alone, the Howard Foundation has committed €1 million to support the continuation of research by Prof Nolan and his team. This support shows yet again that Waterford can be at the centre of global research and can compete successfully internationally.”
Present at the opening, Alicia O'Rourke representing the European Research Council (ERC) said "Excellence in research is a top priority for the European Union. ERC funding helps bring about new and unpredictable discoveries – the kind that can form new industries, markets, and increase our quality of life. By funding top researchers, like Prof Nolan, the ERC is helping to keep Europe on the map of global competitiveness."
Commenting at the launch, Dr Alan Howard, Chairman of the Trustees of the Howard Foundation, England said, “The Howard Foundation is delighted to support financially the building of the Howard Laboratory at Carriganore House. It will be a great advantage to have the study of macular pigments in one location and it will help maintain the tremendous growth taking place in this important and valuable area of research”.
According to Dr Ruaidhrí Neavyn, President of WIT, “The MPRG is a shining example of how academic research can have a real impact on society. Over the years, Prof Nolan has helped countless people struggling with their sight and it is both rewarding and exciting to see his research grow and expand into new areas.”
The Howard Laboratory (Analytical chemical laboratory) and the Darwin Laboratory (Biotechnology Laboratory) are the latest additions to the Vision Research Centre which houses the MPRG. The construction of both laboratories was supported by the Howard Foundation, England, Nutrasight Consultancy Ltd (Waterford Company) and the Waterford Institute of Technology.
Professor Nolan, Principal Investigator of the Macular Pigment Research Group (MPRG) was recently interviewed by...
Professor Nolan interviewed by BBC Future Science
Professor Nolan, Principal Investigator of the Macular Pigment Research Group (MPRG) was recently interviewed by Douglas Heingartner from the BBC about research developments in the MPRG.
The story is now published and can be viewed from the link below.
Professor Beatty was recently interviewed on the TG4 programme entitled "I mBarr do Slainte". The...
Professor Beatty interviewed on I mBarr do Slainte on TG4
Professor Beatty was recently interviewed on the TG4 programme entitled "I mBarr do Slainte". The programme centred around the importance of eye health. To watch this programme in full, please click on the link below:
Countless collisions have occurred due to blind spots created by sun glare and the distance...
Motorists, including truck drivers are being warned of the dangers of sun glare.
Countless collisions have occurred due to blind spots created by sun glare and the distance perception problems that are created. Driving directly against the sun can also block peripheral areas of vision and cause sudden moments of blindness as the sun peeks out from behind surrounding objects.
It can make using the road for pedestrians and cyclists very challenging also as it can be very difficult for motorists to see them.
Like beauty, glare is often in the eye of the beholder. Drivers middle-aged and older are more sensitive to glare than younger drivers because their eyes take longer to adjust to changing light levels.
For example, a 55-year old takes eight times longer to recover from glare than a 16-year-old. As the population ages, the number of older drivers will continue to rise as will the number of complaints about glare.
Lighter-coloured eyes are more sensitive, which means the lighter your eyes are the more glare will bother you. Certain other conditions, such as having had vision-correction surgery that affects the corneas, may also increase your sensitivity to glare.
James Loughman, Professor of Optometry and Vision Science at Dublin Institute of Technology added: “Individuals who suffer dry eyes often find their symptoms worsen during driving. This has the additional effect of increasing glare as a result of ocular irritation and an irregular tear film. Our research at Dublin Institute of Technology has also revealed that macular pigment plays a critical role in glare sensitivity.This pigment, which accumulates in the retina, filters the light as it strikes the retina and removes the components that cause glare much in the way that polarised sunglasses work. In essence, this pigment is the eye’s natural protection against glare”.
Unexpectedly, our diet is an important factor for both tear function and macular pigment protection against glare. Evidence exists, for example, that omega-3 fatty acids have a beneficial effect on tear function. Macular pigment is entirely of dietary origin and is typically deficient in Irish adults due to the lower than average intake of leafy green vegetables such as spinach or kale. This may predispose individuals to increased risk of glare and potentially to certain eye disease such as age-related macular degeneration. Importantly, however, Prof. Loughman states that “our research has shown that dietary supplementation with macular carotenoids in the quantities found in the commercially available supplement, Macushield, can alleviate glare sensitivity, while the use of artificial tears can have similarly beneficial effects on glare disability in the case of persistent dry eye”.
Article sourced from Safedriving.ie http://www.safedriving.ie/606/motorists-get-sun-glare-warning-2/
James Loughman, professor of optometry and vision science at Dublin Institute of Technology, says there...
A professor of optometry has issued a warning about the dangers to road users posed by sun
James Loughman, professor of optometry and vision science at Dublin Institute of Technology, says there is a risk of collisions due to blind spots created by sun glare and the distance perception problems that this creates. He also explained that driving directly against the sun can also block peripheral vision and cause sudden moments of blindness as the sun peeks out from behind surrounding objects. The professor goes on to explain that middle-aged and older drivers are more sensitive to glare than younger drivers, because their eyes take longer to adjust to changing light levels. People with lighter coloured eyes will be bothered more by glare and vision-correction surgery can also increase sensitivity to glare. Professor Loughman said: “Individuals who suffer dry eyes often find their symptoms worsen during driving. This has the additional effect of increasing glare as a result of ocular irritation and an irregular tear film. “Our research also revealed that macular pigment plays a critical role in glare sensitivity. This pigment, which accumulates in the retina, filters the light as it strikes the retina and removes the components that cause glare, in the way that polarised sunglasses work. In essence, this pigment is the eye’s natural protection against glare.”Professor Loughman goes on to say that diet is an important factor for both tear function and macular pigment protection against glare. He said: “Our research has shown that dietary supplementation with macular carotenoids in the quantities found in the commercially available supplement, Macushield, can alleviate glare sensitivity, while the use of artificial tears can have similarly beneficial effects on glare disability in the case of persistent dry eye.” Noel Gibbons, road safety officer for Mayo County Council in Ireland, said: ''We can't change the position of the sun, or the need to travel at certain times, but there are simple steps you can take to ensure you're prepared for these conditions. ''Keep your windscreen clean, both inside and out. Dirty windscreens add to the danger when the sun is low. “If you can't see, slow down accordingly, keeping an eye on the traffic behind, in case the following vehicle doesn't see you against the sun. “Also, beware with these fine evenings (as) there are more pedestrians and cyclists on the road.''
Article sourced from Road Safety GB, Friday 19th September 2014 http://www.roadsafetygb.org.uk/news/3883.html">http://www.roadsafetygb.org.uk/news/3883.html
MPRG Student Rachel Moran spoke today about her research at the 17th Triennial International Carotenoid...
MPRG Student Rachel Moran Presents at 17th Triennial International Carotenoid Symposium in UTAH
MPRG Student Rachel Moran spoke today about her research at the 17th Triennial International Carotenoid Symposium in Utah today. Rachel is also nominated for a presentation award at the conference.
The MPRG attended the opening of the new Netlabs facility in the Carraiganore Campus of...
WIT’s ‘NetLabs’ centre to create 600 jobs by 2019
The MPRG attended the opening of the new Netlabs facility in the Carraiganore Campus of WIT where they showcased their research to date for Minister Ruairi Quinn. Click here to read the full press release from the Irish Independant.
Hi everyone, thank you so much for all the positive feedback following the Nationwide documentary...
Huge response to Nationwide documentary!
Hi everyone, thank you so much for all the positive feedback following the Nationwide documentary on Monday night!
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News story from the European Commission newsletter, 30th January 2014: "News you can use" Professor...
MPRG to be showcased on RTE Nationwide
News story from the European Commission newsletter, 30th January 2014: "News you can use"
Professor John Nolan and his research team in the Macular Pigment Research Group (MPRG) at Waterford Institute of Technology (WIT) are working on how to prevent a condition called age-related macular degeneration (AMD), a condition which affects an estimated 12 million people across Europe.
AMD is the leading cause of irreversible blindness in people over 50 years of age, affecting an estimated 80,000 people in the Republic of Ireland, 500,000 people in the UK and over 12 million sufferers across Europe. This eye disease is particularly frustrating because it results in a loss of central vision. In other words, someone with AMD can see everything except what he or she is looking at, and is therefore unable to read, watch TV, drive, or recognise a loved one’s face.
Professor Nolan's work is being funded by the EU's European Research Council (ERC) to the tune of €1.5 million over 5 years. The research being undertaken at WIT will lead to improvements in eyesight for many sufferers of impaired vision, and potentially be beneficial even for those who are considered to have ‘normal’ vision.
Find out more about Prof Nolan's research project by watching Nationwide RTE TV - Monday 3 February at 19:00
Pictured: Professor John Nolan (back row, right) with Nationwide presenter Helen McInerney (back row, left), the RTE film crew, and MPRG patients.
Kwadwo Akuffo has been awarded the Young Achiever Award at the first edition of the...
Kwadwo Akuffo awarded Young Achiever Award
Kwadwo Akuffo has been awarded the Young Achiever Award at the first edition of the Ghanaian – Irish & Networks Excellence (GINE) Awards. The GINE Awards were organised by the Ghana Union Ireland (GUI) in collaboration with the Ghana Consulate Ireland. The awards ceremony was held on the 28th December, 2013, at the Louis Fitzgerald Hotel, Dublin, to award individuals, organisations and groups demonstrating leadership, selflessness and dedication to the Ghanaian-Irish community within Ireland, and also to raise awareness and funds for GUI youth annual educational and social integration programmes in all regions. Ten different awards were given at the ceremony which included the Young Achiever Award. An awards committee reviewed nominations from Ghanaian-Irish community and network groups in the Republic of Ireland.
Three young people were nominated for the Young Achiever Award, given in recognition of an outstanding young person aged 16-30 years who has broken barriers and currently studying or yet to study at a university; has demonstrated dedication, enthusiasm, commitment and achievement in their chosen field; has excelled academically including extra-curricular activities within the community; and is a good role model amongst peers. His award was presented by Mr. Joe Costello T.D., Minister of State for Trade and Development and Mrs Emer Costello, Member of European Parliament for Dublin.
Kwadwo pictured (left) with Mr. Joe Costello T.D., Minister of State for Trade and Development, and other award winners.
The MPRG welcomes applications from high-achieving academic students who are interested in applying for funding...
Vacancy: Postgraduate Students
The MPRG welcomes applications from high-achieving academic students who are interested in applying for funding to pursue a research PhD or Masters through the Irish Research Council (IRC) Postgraduate scheme 2014/ 2015. Click here for more information on this post and the application process.
Following the Macular Carotenoids Conference 2013, a CRC Press book publication entitled "Carotenoids and Retinal...
Carotenoids and Retinal Disease book release
Following the Macular Carotenoids Conference 2013, a CRC Press book publication entitled "Carotenoids and Retinal Disease" has been released. This publication is a collaboration between the key opinion leaders in the field of macular carotenoids, and was edited by Professors John Nolan and John Landrum.
This book presents an up-to-date, thorough volume devoted to the chemistry, pathobiology, visual science, and medical and public health significance of the macular carotenoids. With contributions from an international group of leading experts, it covers a range of topics, from macular anatomy to clinical trials.
Carotenoids and Retinal Disease
John T. Landrum, Florida International University, Miami, USA
John Nolan, Waterford Institute of Technology, Waterford, Ireland
We are pleased to announce that the new MPRG website (direct link www.mprg.ie) has now...
New MPRG website!
We are pleased to announce that the new MPRG website (direct link www.mprg.ie) has now been launched. New content includes a Photo Gallery, Videos, Research Projects page, amongst other more detailed information. Remember to check out the News page for frequent updates, as well as our Facebook page!
Professors John Nolan and Stephen Beatty gave an interview at ARVO (Association of Research in...
Interview: Advances in Macular Carotenoids
Professors John Nolan and Stephen Beatty gave an interview at ARVO (Association of Research in Vision and Ophthalmology) Conference 2013, Seattle, USA. They discussed the current MPRG research projects and the importance of the central macular carotenoid, meso-zeaxanthin. This interview is now available and can be viewed here: Advances in Macular Carotenoids
The MPRG attended the Macular Carotenoids Conference 2013 at Cambridge University, UK. This conference was...
Macular Carotenoids Conference, Cambridge
The MPRG attended the Macular Carotenoids Conference 2013 at Cambridge University, UK. This conference was held to provide a forum where macular carotenoid researchers could explore up-to-date and evidence-based hypotheses, and discuss the supporting research data into the role of the macular carotenoids in age-related macular degeneration (AMD), vision, and cognitive function. The MPRG PhD students, Kwadwo Akuffo, Jessica Dennison, Katie Meagher, Rachel Moran and Kate Loskutova all presented their data in the form of poster presentations. The MPRG Principal Investigator, Professor John Nolan, was chair of this conference, and gave several well-received lectures.
Pictured: Kwadwo Akuffo presenting his poster on the "Prevalence of sight-threatening ocular pathology in Ireland: The Irish Longitudinal Study on Ageing".
The MPRG is pleased to announce that Kwadwo Akuffo, MPRG PhD student, received an invitation...
Kwadwo presents CREST project at Global Seminar in Ethiopia
The MPRG is pleased to announce that Kwadwo Akuffo, MPRG PhD student, received an invitation from the Director of ISC (Intelligence in Science, based in Brussels), to present the CREST project at the "Global Science Collaboration: Science Capacity Building in Africa" seminar. This event, held at the Irish Embassy in Addis Ababa, Ethiopia, brought together international decision-makers, researchers, academic community and industry leaders to discuss issues and topics relating to developing human and technological capacity through science collaboration. The CREST project is an example of on-going EU Africa science cooperation and collaboration and it has potential application in Africa. Kwadwo spoke on the topic “Central Retinal Enrichment Supplementation Trials (CREST): a clinical trial into nutrition and age-related macular degeneration.”
Pictured: Kwadwo Akuffo (fifth from right) with delegates at the Irish Embassy in Addis Ababa, Ethiopia
MPRG postgraduate student Jessica Dennison has been awrded a travel grant from Heidelberg Engineering for...
Heidelberg Engineering grant awarded to Jessica Dennison
MPRG postgraduate student Jessica Dennison has been awrded a travel grant from Heidelberg Engineering for her work with their device the Heidelberg Engineering Spectralis HRA+OCT, a specialised instrument for assessing eye health in vivo. This data will be published as a peer-reviewed manuscript entitled “Concordance of macular pigment measurements obtained using customized heterochromatic flicker photometry, dual-wavelength autofluorescence, and single-wavelength reflectance.”
Of interest, the Spectralis used in the MPRG vision laboratory is the same device which is currently being used by NASA in the International Space Station to monitor the astronauts' visual health. Read more here: Spectralis in Space
Pictured: Jessica Dennison measuring a patient's macular pigment using the Spectralis.
The Macular Pigment Research Group is proud to announce that Kwadwo Akuffo successfully won a...
Kwadwo wins place on prestigious Cochrane Training course
The Macular Pigment Research Group is proud to announce that Kwadwo Akuffo successfully won a place on the prestigious Cochrane Training Courses 2013 after a competitive application process. The Health Research Board and the HSC Research & Development Division in Northern Ireland, in association with the Training Team of the UK Cochrane Centre, offered two courses: ‘Introduction to Cochrane’ and the ‘Cochrane Systematic Review Course’. Kwadwo was awarded this training following a highly competitive application process. The aim of the Cochrane Training Courses is to build awareness and capacity in conducting systematic review in Ireland.
The Macular Pigment Research Group is proud to announce that Kwadwo Akuffo won a place...
Kwadwo wins Best Poster Prize at WIT Research Day
The Macular Pigment Research Group is proud to announce that Kwadwo Akuffo won a place the Best Poster Delegates' Choice Award at the Waterford Institute of Technology Research Day 2013. Kwadwo’s poster presented the “Central Retinal Enrichment Supplementation Trials: Design and Methodology.”
Pictured: Kwadwo Akuffo receives his award from Dr. Ruaidhrí Neavyn, President, Waterford Institute of Technology
Professor John Nolan, Principal Investigator of Waterford Institute of Technology’s (WIT) Macular Pigment Research Group...
Professor John Nolan: Trinity Affiliation
Professor John Nolan, Principal Investigator of Waterford Institute of Technology’s (WIT) Macular Pigment Research Group (MPRG) has recently been appointed Professor (Adjunct Assistant) at Trinity College Dublin (TCD), in recognition and support of his ongoing academic collaboration with the TCD-based TILDA study.
TILDA is an acronym for ‘The Irish LongituDinal Study on Ageing’, designed to investigate the health, social and economic circumstances of the ageing Irish population, and includes 8,178 participants aged 50 years and over.
Professor Nolan is also a Fulbright Scholar, Howard Fellow and European Research Council (ERC) Fellow.
The Macular Pigment Research Group, led by Professor Nolan, is based at the Vision Research Centre, Carriganore House at WIT’s West Campus and studies the role of nutrition in vision and in the prevention of blindness. To date, Professor Nolan has secured €5 million in research funding in support of these studies and he is currently managing several projects.
Professor Nolan has successfully supervised ten students to MSc, PhD and MD level, and is currently supervising six PhD candidates as part of ongoing projects at the MPRG. He has presented at over 70 international scientific conferences and has published 61 peer-reviewed scientific papers on his area of research (1,001 citations, H index 17). Professor Nolan is also Chair of the international Macular Carotenoids Conference, which is held at Downing College, Cambridge University, UK (http://www.macularcarotenoids.org).
Professor Nolan and his colleague, Professor Stephen Beatty (Director of MPRG and Institute of Eye Surgery, Whitfield Clinic; and an Adjunct Professor of TCD) have been collaborating with Professor Rose Anne Kenny (the Principal Investigator of the TILDA study) at TCD since 2007. This fruitful collaboration between WIT and TCD has already led to several landmark peer-reviewed publications.
Professor Nolan and Professor Beatty are leading the vision-related component of TILDA.
Professor Nolan said, “This is a great honour for me, my research group, and my family to be recognised in this way. The TILDA project has required a gigantic effort from all the researchers involved, and we are fascinated with the results it is already producing.
“This project is vital to inform healthcare policy makers, as the ageing population continues to represent an ever increasing proportion of the overall population. The increase in life expectancy presents many challenges to society, and only if we understand the socio-economic implications of an ageing society can we hope to accommodate the changing needs of Ireland.”
See www.tilda.ie for more details.
The Macular Pigment Research Group is proud to announce that Sarah Sabour-Pickett has successfully passed...
Sarah Sabour-Pickett graduates!
The Macular Pigment Research Group is proud to announce that Sarah Sabour-Pickett has successfully passed her PhD Viva and celebrated her graduation recently, having completed her studies with the MPRG on "Visual Performance and its Response to Intervention in Subjects with Age-Related Macular Degeneration". We wish her every success with her future career.
On the 8th October 2012 the MPRG met the European Commissioner for Research, Innovation and...
European Commissioner visits WIT
On the 8th October 2012 the MPRG met the European Commissioner for Research, Innovation and Science, Máire Geoghegan-Quinn, who was visiting the Waterford Institute of Technology. The Commissioner visited the Carriganore West Campus, where the MPRG's Vision Research Centre is based, and met some of the researchers here. Dr. John Nolan updated the Commissioner on the progress of the European Research Council-funded CREST Project, and the ongoing patient recruitment for the research studies.
Pictured above from left to right: Sarah O'Regan (MPRG Research Assistant), Máire Geoghegan-Quinn (European Commissioner for Research, Innovation and Science), Dr. Willie Donnelly (WIT Head of Research), Kwadwo Akuffo (MPRG PhD student), Dr. John Nolan (MPRG Principal Investigator), Jessica Dennison (MPRG PhD student)
Macular Pigment Research Group
Vision Research Centre
Waterford Institute of Technology
West Campus, Carriganore
(00353) 051 845505