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Dr. Mike Kinsella

Title:

Lecturer in Chemistry/Organic Chemistry & Researcher, PMBRC

School/ Department:

School of Science & Computing - Dept of Science

Room Name/ Num:

B30 1969 - Main Building

Campus:

Main Campus

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My Biography

Dr Mike Kinsella is a Lecturer in Chemistry/Organic Chemistry at the Department of Science, WIT and researcher at the Pharmaceutical and Molecular Biotechnology Research Centre (PMBRC) where he is managing two large European funded projects, Wales Ireland Network for Scientific Skills (WINSS) and High Potency Dermatologicals (HIPODERM).

Dr Kinsella received a BSc (Hons) Degree in Applied Chemistry with Quality Management (first class honours) in 2003 and a PhD in Organic and Analytical chemistry from WIT in 2011, respectively. The subject of his IRCSET-funded PhD thesis was the Synthesis of Artificial Receptor Motifs for Anion Binding and Organocatalysis and during this time he gained experience working at collaborator labs at University College Dublin. Dr Kinsella conducted his postdoctoral research in the School of Food and Nutritional Sciences, UCC from October 2010 to June 2013 on the novel application of state-of-the art low and high resolution LC-MS technology for identification and analysis of biofluids from biological sources with a particular focus on metabolomics, proteomics and quantitation of vitamin D metabolites in human serum. In June 2013, he returned to WIT to manage two large EU funded research projects (WINSS Interreg 4A project and HIPODERM Fp7 Marie Curie IAPP project) in addition to course development and validation, lecturing and working on a number of industrial research projects. In September 2014, he became an academic staff member in the Department of Science, WIT working as a lecturer in chemistry/organic chemistry while simultaneously being involved in project management and working on various projects for industry partners such as Bausch & Lomb, Waters, Xeolas and Arran Chemicals.

Dr Kinsella is currently project manager of the HIPODERM EU Fp7 project, a collaborative research project investigation the delivery of drugs into the through the human skin barrier for treatment of conditions such as skin cancer. He is also co-PI on an Enterprise Ireland Innovation Partnership project investigating novel extraction techniques for isolation of high value components from processing streams and is currently supervising one postdoctoral researcher. Dr Kinsella has secured over €280,000 in research funding to date and has published peer review journal articles in the area of organic metal-free catalysts and applications of LC-MS in biological and clinical applications.

Dr Kinsella is currently undertaking a Masters in Teaching and Learning in Further and Higher Education at WIT and has completed modules in Academic Enquiry, Educational Theory, Practical Pedagogy 1, Curriculum & Assessment and Research Supervisory Skills.

Research

Research interests

Chemistry
Organic Chemistry
Supramolecular Chemistry
Organic Synthesis
Polymer catalysts
Analytical Chemistry
Separation science
Liquid chromatography-mass spectroscopy and applications
Nuclear Magentic Resonance spectroscopy and applications
Biomarker identification
Vitamin D
Extraction of Functional Materials

 

Current Funded Research Projects

Extraction and identification of high value components from processing streams.

Role – PI

Project Researcher – Postdoctoral researcher – Dr Prashant Musmade

 

Grant history

EI-IPP (IP-2014-0463): Michael Kinsella, Laurence Fitzhenry, Niall O’Reilly, Orla O’Donovan & Peter McLoughlin, Confidential (2014) €210,633
IRCSET PhD scholarship: Michael Kinsella, The Development of Novel Hydrogen Bonding Organocatalysts for Asymmetric Synthesis (2007) €72,000

Teaching

Department of Science, WIT

10 credit Level 9 Modules Developed 2013-2014

Process Analytical Technology & Statistics – Programme Development Team Leader

International Regulatory Affairs – Programme Development Team Leader

Advanced Spectroscopic Techniques – Programme Development Team

Advanced Quality Methodologies – Programme Development Team

Data Analysis & Research Methodologies – Programme Development Team

Biopharmaceutical Science and Cell Culture – Programme Development Team

Food Safety & Analytical microbiology – programme Development Team

 

Coordinated update and CE3 validation of Level 9 MSc in Analytical Science with Quality Management 2013-2014

 

Coordinated delivery of Advanced Chromatographic Techniques, Advanced Spectroscopic Techniques and Advanced Materials Characterisation and MSc in Analytical Science with Quality Management 2013-2014

 

 

Modules Taught

 

MSc in Analytical Science with Quality Management

Advanced Spectroscopic Techniques

 

BSc(H) in Pharmaceutical Science/ BSc (H) in Applied Biology with QM/ General Chemistry/ BSc in Agriculture

Pharmaceutical Organic Chemistry

Pharmaceutical Organic Chemistry IV

Organic Chemistry and Advanced Spectroscopic Techniques

Pharmaceutical Natural Products

Pharmaceutical Biotechnology

Inorganic Chemistry

Introduction to Biotechnology and Pharmaceutical Science

Research projects – Year 3 and Year 4

Physical & Organic Chemistry

Information and Communications Technology

Introductory Chemistry

Chemistry for Land Scientists

Organic Chemistry and Biomolecules

Good Laboratory Practice & Core Skills

 

BSc in Nutritional Sciences, UCC 2012-2013

Year 4 Research projects

Professional

Honours and awards

Year Title Awarding body
2007 EMBARK PhD Scholarship: “The Development of Novel Hydrogen Bonding Organocatalysts for Asymmetric Synthesis” IRCSET
2010 Developed and fully validated extraction and LC-MS/MS method for analysis of 25-hydroxyvitamin D in human serum at UCC – traceable to NIST higher order Reference Method Procedure and certified by Centre for Disease Control (CDC) at National Institute of Health (NIH), USA. One of only two labs in Europe to achieve certification. CDC – Vitamin D Standardization Certificaton Programme
2004 Reagecon sponsored award for Chemistry in first year of BSc for highest overall chemistry results Reagecon / WIT
2005 Annual Eurachem Analytical Measurement Competition Eurachem
2003 Award for achieving over 500 points in Leaving Certificate WIT
2003 Overall academic achievement award Waterpark College, Waterford


Professional associations

Association Function From/To
Irish Mass Spectrometry Society Commitee member 2014-present
WIT Research Staff Forum Member 2015-present
Departmental Research Committee Member 2014-present
Institute of Chemistry Ireland Associate member 2005-present
UCC Research Staff Association Member 2010 - 2013

 

Commitees

Commitee Function From/To
Departmental research committee   2010-present

 

Other activities

Currently Undertaking MA in Teaching & Learning in Further and Higher Education,WIT. 2013-present

Publications

Journal articles

Kinsella, Michael; Duggan, Patrick G.; Muldoon, Jimmy; Eccles, Kevin S.; Lawrence, Simon E.; Lennon, Claire M.; Synthesis and NMR Binding Studies towards Rational Design of a Series of Electron-Withdrawing Diamide Receptors/Organocatalysts (2011) European Journal of Organic Chemistry, 6, 1125-1132

Kinsella, Michael; Duggan, Patrick G.; Lennon, Claire M.; Screening of simple N-aryl and N-heteroaryl pyrrolidine amide organocatalysts for the enantioselective aldol reaction of acetone with isatin (2011 Tetrahedron-Asymmetry, 22, 13, 1423-1433.

O’ Connell Motherway, Mary, Kinsella, Michael, Fitzgerald, Gerald F., Van Sinderen; Transcriptional and Functional Characterization of genetic elements involved in galacto-oligosaccharide utilisation by Bifidobacterium breve UCC2003 (2013), Microbial Biotechnology, 6, (1), 67-79.

Cashman, Kevin D, Kiely, Mairead, Kinsella, Michael et al. Evaluation of Vitamin D Standardization Program protocols for standardizing serum 25-hydroxyvitamin D data: a case study of the program's potential for national nutrition and health surveys (2013), American Journal of Clinical Nutrition, 97, (6), 1235-1242.

Joyce, Susan A., MacSharry, John, Casey, Patrick, Kinsella, Michael, Murphy, Eileen F., Shanahan, Fergus, Hill, Colin, Gahan, Cormac G.M. Bacterial bile salt hydrolase regulates host energy metabolism and weight gain (2014), PNAS, 111, (20), 7421-7426

Cashman, Kevin D, Kinsella, Michael et al, The 3 epimer of 25-hydroxycholecalciferol is present in the circulation of the majority of adults in a nationally representative sample and has endogenous origins (2014), Journal of Nutrition, 144, (7), 1050-1057.

Cashman, Kevin D, Kinsella, Michael, McNulty, Breige, Walton, Janette, Gibney, Michael J, Flynn, Albert, Kiely, Mairead. Dietary vitamin D2 – a potentially under-estimated contributor to vitamin D nutritional status of adults? (2014), British Journal of Nutrition, 112, (2), 193-202.

Cashman, Kevin D, Hayes, Aoife, O’Donovan, Sinead M., Zhang, Joy Y, Kinsella, Michael, Galvin, Karen, Kiely, Mairead, Seamans, Kelly M., Dietary calcium does not interact with vitamin D3 in terms of determining the response and catabolism of serum 25-hydroxyvitamin D during winter in older adults, (2014), American Journal of Clinical Nutrition, 99, (6), 1414-1423

Nolan, James A, Kinsella, Michael, Hill, C., Joyce, Susan A, Gahan, Cormac G; Antibacterial activity of rosuvastatin correlates with reduced mevalonate formation (2015), Letters in Applied Microbiology, Article submitted.

Conference Proceedings

Kinsella, Michael et al., “Overview of HIPODERM Transdermal Drug delivery project”, PPP conference, La Grande Motte, France, April 2014 (Oral Presentation)

Kinsella, Michael, Frisby, June  et al., “Wales Ireland Network for Scientific Skills (WINSS) - Regional Skills Enhancement Programme, Dublin, May 2014, (Oral Presentation).

Kinsella Michael, Cashman K et al, “Vitamin D Standardization programme-UCC Perspective”, UCC VDSP Meeting, University College Cork, February 2011 (Oral presentation).


Kinsella, Michael, Lennon, Claire, Muldoon, Jimmy, “Simple bisamide anion receptors: Remarkable increase in binding through the introduction of 3,5-biss(trifluoromethyl)phenyl groups”, 16th European Symposium on Organic Chemistry, Prague, Czech Republic, 12th-16th July 2009 (Poster Presentation)

Kinsella, Michael, Lennon, Claire, Muldoon, Jimmy, “Novel bisamides as multipurpose molecules: anion receptors and organocatalysts”, Innovation Fuelling the Smart Economy, Dublin, 25th September 2009 (Poster Presentation).